Mouse Anti-LRG1 Recombinant Antibody (2F5.A2) (CBMAB-L2017-YJ)

Name: Mouse Anti-LRG1 Recombinant Antibody (2F5.A2)
SKU: CBMAB-L2017-YJ
Rating: 5 (1 reviews)

See all LRG1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

2F5.A2

Application

ELISA

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, 0.1% BSA

Preservative

0.02% Sodium Azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

LRG1

Introduction

The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to function in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation.

Entrez Gene ID

116844

UniProt ID

P02750

Alternative Names

LRG; HMFT1766; leucine-rich alpha-2-glycoprotein; 1300008B03Rik; 2310031E04Rik; leucine rich alpha 2 glycoprotein

Biological Process

Brown fat cell differentiationIEA:Ensembl
Keratinocyte migrationManual Assertion Based On ExperimentIMP:BHF-UCL
Leukocyte adhesion to vascular endothelial cellManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of angiogenesisManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of endothelial cell proliferationManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of epithelial cell proliferation involved in wound healingManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of epithelial to mesenchymal transitionManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of keratinocyte proliferationManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of transforming growth factor beta receptor signaling pathwayManual Assertion Based On ExperimentIDA:BHF-UCL
Response to bacteriumIEA:Ensembl
Wound healing, spreading of epidermal cellsManual Assertion Based On ExperimentIMP:BHF-UCL

Cellular Location

Secreted

Grzesiak, L., Amaya-Garrido, A., Feuillet, G., Malet, N., Swiader, A., Sarthou, M. K., ... & Laffargue, M. (2023). Leucine-Rich Alpha-2 Glycoprotein 1 Accumulates in Complicated Atherosclerosis and Promotes Calcification. International Journal of Molecular Sciences, 24(22), 16537.

Sarkar, A., Chakraborty, D., Kumar, V., Malhotra, R., & Biswas, S. (2022). Upregulation of leucine-rich alpha-2 glycoprotein: A key regulator of inflammation and joint fibrosis in patients with severe knee osteoarthritis. Frontiers in Immunology, 13, 1028994.

Zou, Y., Xu, Y., Chen, X., Wu, Y., Fu, L., & Lv, Y. (2022). Research progress on leucine-rich alpha-2 glycoprotein 1: a review. Frontiers in pharmacology, 12, 809225.

Lin, M., Liu, J., Zhang, F., Qi, G., Tao, S., Fan, W., ... & Zhou, F. (2022). The role of leucine-rich alpha-2-glycoprotein-1 in proliferation, migration, and invasion of tumors. Journal of Cancer Research and Clinical Oncology, 1-9.

Liu, J. J., Pek, S. L., Liu, S., Wang, J., Lee, J., Ang, K., ... & Lim, S. C. (2021). Association of plasma leucine-rich alpha-2 glycoprotein 1 (LRG1) with all-cause and cause-specific mortality in individuals with type 2 diabetes. Clinical Chemistry, 67(12), 1640-1649.

Javaid, F., Pilotti, C., Camilli, C., Kallenberg, D., Bahou, C., Blackburn, J., ... & Chudasama, V. (2021). Leucine-rich alpha-2-glycoprotein 1 (LRG1) as a novel ADC target. RSC chemical biology, 2(4), 1206-1220.

Nambu, M., Masuda, T., Ito, S., Kato, K., Kojima, T., Daiko, H., ... & Ohtsuki, S. (2019). Leucine-rich alpha-2-glycoprotein 1 in serum is a possible biomarker to predict response to preoperative chemoradiotherapy for esophageal cancer. Biological and Pharmaceutical Bulletin, 42(10), 1766-1771.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-LRG1 Recombinant Antibody (2F5.A2)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

LRG1 Matched Antibody Pair (699) (CAT#: APMAB-699LY)

Related Products

Mouse Anti-LRG1 Recombinant Antibody (13A50) (CAT#: CBMAB-L2014-YJ)

Mouse Anti-LRG1 Recombinant Antibody (CBYCL-455) (CAT#: CBMAB-L0356-YC)

Mouse Anti-LRG1 Recombinant Antibody (2E3) (CAT#: CBMAB-L2016-YJ)

Mouse Anti-LRG1 Recombinant Antibody (A928) (CAT#: CBMAB-AP4267LY)

Mouse Anti-LRG1 Recombinant Antibody (1H1) (CAT#: CBMAB-L2015-YJ)

Mouse Anti-LRG1 Recombinant Antibody (A927) (CAT#: CBMAB-AP4264LY)

LRG1 Matched Antibody Pair (699) (CAT#: APMAB-699LY)

Mouse Anti-LRG1 Recombinant Antibody (CBYCL-453) (CAT#: CBMAB-L0354-YC)

Rabbit Anti-LRG1 Recombinant Antibody (
7A1) (CAT#: V2LY-0725-LY1080)

Mouse Anti-LRG1 Recombinant Antibody (A926) (CAT#: CBMAB-AP4262LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry