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Mouse Anti-LRGUK Recombinant Antibody (7B4) (CBMAB-L2020-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Leucine Rich Repeats And Guanylate Kinase Domain Containing (LRGUK). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all LRGUK antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
7B4
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
LRGUK (NP_653249, 721 a.a. ~ 825 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: YFKPPFGPYP EKSGKDSLVS MKCSLFRFCP WSKELPFQPP EGSISSHLGS GASDSETEET RKALPIQSFS HEKESHQHRQ HSVPVISRPG SNVKPTLPPI PQGRR.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 721-825

Target

Full Name
leucine-rich repeats and guanylate kinase domain containing
Introduction
Gene Ontology (GO) annotations related to this gene include kinase activity. An important paralog of this gene is LRRC9.
Entrez Gene ID
136332
UniProt ID
Q96M69
Alternative Names
CFAP246; leucine-rich repeat and guanylate kinase domain-containing protein
Function
Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis.
Biological Process
Axoneme assemblyISS:UniProtKB
Cell differentiationIEA:UniProtKB-KW
SpermatogenesisISS:UniProtKB
Cellular Location
Cytoplasmic vesicle, secretory vesicle, acrosome
Cytoplasm, cytoskeleton
Cytoplasm, cytoskeleton, cilium basal body
Localizes to the acrosome and acroplaxome in round spermatids. Localizes to the manchette during spermiogenesis. Also found in the basal body of elongating spermatids, and in primary cilia of somatic cells.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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