Mouse Anti-LRGUK Recombinant Antibody (7B4) (CBMAB-L2020-YJ)

Name: Mouse Anti-LRGUK Recombinant Antibody (7B4)
SKU: CBMAB-L2020-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

7B4

Application

ELISA, WB

Immunogen

LRGUK (NP_653249, 721 a.a. ~ 825 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: YFKPPFGPYP EKSGKDSLVS MKCSLFRFCP WSKELPFQPP EGSISSHLGS GASDSETEET RKALPIQSFS HEKESHQHRQ HSVPVISRPG SNVKPTLPPI PQGRR.

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 721-825

More Infomation

Target

Full Name

leucine-rich repeats and guanylate kinase domain containing

Introduction

Gene Ontology (GO) annotations related to this gene include kinase activity. An important paralog of this gene is LRRC9.

Entrez Gene ID

136332

UniProt ID

Q96M69

Alternative Names

CFAP246; leucine-rich repeat and guanylate kinase domain-containing protein

Function

Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis.

Biological Process

Axoneme assemblyISS:UniProtKB
Cell differentiationIEA:UniProtKB-KW
SpermatogenesisISS:UniProtKB

Cellular Location

Cytoplasmic vesicle, secretory vesicle, acrosome
Cytoplasm, cytoskeleton
Cytoplasm, cytoskeleton, cilium basal body
Localizes to the acrosome and acroplaxome in round spermatids. Localizes to the manchette during spermiogenesis. Also found in the basal body of elongating spermatids, and in primary cilia of somatic cells.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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