Mouse Anti-LRP11 Recombinant Antibody (CBYJL-1968) (CBMAB-L2048-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Ldl Receptor Related Protein 11 (LRP11). The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all LRP11 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBYJL-1968

Antibody Isotype

IgG

Application

WB, IP, IF, ELISA

Basic Information

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

LDL receptor related protein 11

Introduction

An important paralog of this gene is KIAA0319.

Entrez Gene ID

84918

UniProt ID

Q86VZ4

Alternative Names

MANSC3; bA350J20.3; low-density lipoprotein receptor-related protein 11; LRP-11

Biological Process

Multicellular organismal response to stressIEA:Ensembl
Response to coldIEA:Ensembl
Response to heatIEA:Ensembl
Response to immobilization stressIEA:Ensembl
Response to mechanical stimulusIEA:Ensembl
Response to starvationIEA:Ensembl
Response to water deprivationIEA:Ensembl

Cellular Location

Membrane

Topology

Extracellular: 38-450
Helical: 451-473
Cytoplasmic: 474-500

References

Pei, J., Wang, H., Zhang, Y., & Chen, T. (2023). The Role of Low-Density Lipoprotein Receptor-Associated Protein LRP11 in the Development of Hepatocellular Carcinoma. Science of Advanced Materials, 15(7), 972-978.

Gu, F., Xu, F., Pan, Z., Shi, L., Yu, J., Song, F., ... & Sun, M. (2023). An integrative pan-cancer analysis illustrating the key role of LRP11 in cervical cancer. Medicine, 102(11).

Li, P., Zeng, Y., Chen, Y., Huang, P., Chen, X., & Zheng, W. (2022). LRP11-AS1 promotes the proliferation and migration of triple negative breast cancer cells via the miR-149-3p/NRP2 axis. Cancer Cell International, 22(1), 116.

Gan, S., Ye, J., Li, J., Hu, C., Wang, J., Xu, D., ... & Cui, X. (2020). LRP11 activates β-catenin to induce PD-L1 expression in prostate cancer. Journal of Drug Targeting, 28(5), 508-515.

Wang, Y., Han, S., You, X., Shi, X., Liu, L., Sun, Y., ... & Zhang, Y. (2019). The role of low density lipoprotein receptor-related protein 11 as a tumor promoter in cervical cancer. Cancer Management and Research, 8081-8093.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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SDS
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Second antibody and isotype control

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