Mouse Anti-LRRN2 Recombinant Antibody (CBYCL-494) (CBMAB-L0395-YC)

Provided herein is a Mouse monoclonal antibody against Human LRRN2. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all LRRN2 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBYCL-494

Antibody Isotype

IgG2b, κ

Application

ELISA, WB

Basic Information

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 532-630

Target

Full Name

Leucine Rich Repeat Neuronal 2

Introduction

LRRN2 belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas.

Entrez Gene ID

10446

UniProt ID

O75325

Alternative Names

FIGLER7; GAC1; LRANK1; LRRN5

Biological Process

Cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Membrane

Topology

Extracellular: 19-630
Helical: 631-651
Cytoplasmic: 652-713

References

Tomiyama, T., Yamamoto, T., Takahama, S., Toshima, T., Itoh, S., Harada, N., ... & Yoshizumi, T. (2022). Up‐regulated LRRN2 expression as a marker for graft quality in living donor liver transplantation. Hepatology Communications, 6(10), 2836-2849.

Ning, S., Shi, C., Zhang, H., & Li, J. (2021). Identification of triple gene fusion ALK-LRRN2, LTBP1-ALK, and HIP1-ALK in advanced lung adenocarcinoma and response to alectinib: A case report. Medicine, 100(51).

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Datasheet
SDS
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Second antibody and isotype control

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