Rat Anti-Ly6c1 Recombinant Antibody (CBYCL-562) (CBMAB-L0463-YC)

Name: Rat Anti-Ly6c1 Recombinant Antibody (CBYCL-562)
SKU: CBMAB-L0463-YC
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Rat

Specificity

Mouse

Clone

CBYCL-562

Antibody Isotype

IgG2a

Application

IHC, IP

Basic Information

Specificity

Mouse

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Introduction

Ly6C is a member of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by aglycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction.

Entrez Gene ID

17067

UniProt ID

P0CW02

Alternative Names

Ly 6c; Ly6c protein; Ly-6C; Ly6c1; Ly6c2; Lymphocyte antigen 6 complex; Lymphocyte antigen 6 complex locus C; Lymphocyte antigen 6C; Lymphocyte antigen 6C1; Lymphocyte antigen 6C2; Lymphocyte antigen Ly 6C; CD59_HUMAN

Biological Process

Acetylcholine receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

More Infomation

References

Shay, T. F., Sullivan, E. E., Ding, X., Chen, X., Ravindra Kumar, S., Goertsen, D., ... & Gradinaru, V. (2023). Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors. Science Advances, 9(16), eadg6618.

Morimoto, J., Matsumoto, M., Miyazawa, R., Oya, T., Tsuneyama, K., & Matsumoto, M. (2022). No major impact of two homologous proteins Ly6C1 and Ly6C2 on immune homeostasis. ImmunoHorizons, 6(3), 202-210.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

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Rat Anti-Ly6c1 Recombinant Antibody (CBYCL-561) (CAT#: CBMAB-L0462-YC)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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