Mouse Anti-LY6H Recombinant Antibody (CBYJL-2208) (CBMAB-L2439-YJ)

Name: Mouse Anti-LY6H Recombinant Antibody (CBYJL-2208)
SKU: CBMAB-L2439-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYJL-2208

Application

ELISA, WB

Immunogen

LY6H (AAH28894, 26 a.a. ~ 140 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: LWCQDCTLTT NSSHCTPKQC QPSDTVCASV RITDPSSSRK DHSVNKMCAS SCDFVKRHFF SDYLMGFINS GILKVDVDCC EKDLCNGAAG AGHSPWALAG GLLLSLGPAL LWAGP.

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 26-140

More Infomation

Target

Full Name

lymphocyte antigen 6 complex, locus H

Introduction

Among its related pathways are Metabolism of proteins and Post-translational modification- synthesis of GPI-anchored proteins.

Entrez Gene ID

4062

UniProt ID

O94772

Alternative Names

NMLY6; lymphocyte antigen 6H; ly-6H; lymphocyte antigen 6 complex, locus H

Function

Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.

Biological Process

Acetylcholine receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Animal organ morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Cell membrane

Upadhyay, G. (2019). Emerging role of lymphocyte antigen-6 family of genes in cancer and immune cells. Frontiers in immunology, 10, 819.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-LY6H Recombinant Antibody (3E10) (CAT#: CBMAB-L2440-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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