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Mouse Anti-LY6H Recombinant Antibody (CBYJL-2208) (CBMAB-L2439-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Lymphocyte Antigen 6 Family Member H (LY6H). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all LY6H antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJL-2208
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
LY6H (AAH28894, 26 a.a. ~ 140 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: LWCQDCTLTT NSSHCTPKQC QPSDTVCASV RITDPSSSRK DHSVNKMCAS SCDFVKRHFF SDYLMGFINS GILKVDVDCC EKDLCNGAAG AGHSPWALAG GLLLSLGPAL LWAGP.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 26-140

Target

Full Name
lymphocyte antigen 6 complex, locus H
Introduction
Among its related pathways are Metabolism of proteins and Post-translational modification- synthesis of GPI-anchored proteins.
Entrez Gene ID
4062
UniProt ID
O94772
Alternative Names
NMLY6; lymphocyte antigen 6H; ly-6H; lymphocyte antigen 6 complex, locus H
Function
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.
Biological Process
Acetylcholine receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Animal organ morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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