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Mouse Anti-LY75 Recombinant Antibody (RC38) (CBMAB-D2119-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Lymphocyte antigen 75 (LY75). The antibody can be used for immunoassay techniques, such as IHC-Fr, IHC-P.
See all LY75 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
RC38
Antibody Isotype
IgG1
Application
IHC-Fr, IHC-P

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
lymphocyte antigen 75
Introduction
LY75 has broad expression in lymph node (RPKM 17.2), appendix (RPKM 13.2) and 17 other tissues.
Entrez Gene ID
4065
UniProt ID
O60449
Alternative Names
CD205; LY-75; CLEC13B; DEC-205; GP200-MR6
Function
Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity).
Causes reduced proliferation of B-lymphocytes.
Biological Process
EndocytosisIEA:UniProtKB-KW
Immune responseManual Assertion Based On ExperimentTAS:ProtInc
Inflammatory responseManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
Topology
Extracellular: 28-1666
Helical: 1667-1691
Cytoplasmic: 1692-1722
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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