Mouse Anti-M. tuberculosis hspX Recombinant Antibody (CBMC-C0129) (CBMAB-V208-0824-CQ)

Name: Mouse Anti-M. tuberculosis hspX Recombinant Antibody (CBMC-C0129)
SKU: CBMAB-V208-0824-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBMC-C0129

Application

ELISA, WB

Immunogen

Soluble extract (PPD) of M. tuberculosis

Specificity

M. tuberculosis, M. bovis

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Preservative

0.09% sodium azide

Concentration

0.1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

alpha-crystallin

Introduction

Acts as a chaperone, as it has a significant ability to suppress the thermal denaturation of alcohol dehydrogenase. Cells overexpressing this gene grow more slowly than wild-type cells, and are less susceptible to autolysis following saturation of the culture in vitro, suggesting this protein may slow down the growth rate of M.tuberculosis in culture and by extension during macrophage infection.

Entrez Gene ID

887579

UniProt ID

P9WMK1

Alternative Names

acr; hspX; alpha-crystallin;

Function

Biological Process

Cellular response to hypoxiaManual Assertion Based On ExperimentIEP:MTBBASE
Cellular response to starvationManual Assertion Based On ExperimentIEP:MTBBASE
Negative regulation of growthManual Assertion Based On ExperimentIMP:MTBBASE
Protein autophosphorylationManual Assertion Based On ExperimentIDA:MTBBASE
Protein foldingManual Assertion Based On ExperimentIDA:MTBBASE
Response to heatManual Assertion Based On ExperimentIDA:MTBBASE
Response to hostManual Assertion Based On ExperimentIEP:MTBBASE
Response to host immune responseManual Assertion Based On ExperimentIEP:MTBBASE
Response to hypoxiaManual Assertion Based On ExperimentIDA:MTBBASE
Response to iron ionManual Assertion Based On ExperimentIEP:MTBBASE
Response to nitrosative stressManual Assertion Based On ExperimentIEP:MTBBASE

Cellular Location

Cytoplasm
Secreted, cell wall
Probably the external side of the cell wall; the protein is very abundant in older organisms and surface coating could be the result of autolysis of older organisms.

PTM

Multiple forms of this protein exist in 2D-gels. The differences between them has not been examined.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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