Mouse Anti-M2 Recombinant Antibody (10F6) (CBMAB-0011-CN)

This product is a mouse antibody that recognizes M2 of Reovirus T3D. The antibody 10F6 can be used for immunoassay techniques such as: ELISA, IP, WB.

Datasheet

SDS

Host Species

Mouse

Application

ELISA, IP, WB

Immunogen

Type 3 Dearing (T3D)

Antibody Isotype

IgG2b, κ

Specificity

Reovirus T3D

Clone

10F6

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Introduction

Major outer capsid protein involved in host cell membrane penetration. In the endocytic compartment, outer-capsid protein sigma-3 is removed by cathepsin proteases, which exposes the viral membrane-penetration protein mu-1. Both myristoylated peptides mu-1N and phi are released during infectious subvirion particles (ISVP) formation in the endosome. They associate with host membranes and mu-1N induces permeabilization and delivery of transcriptionally active viral particles into the host cell cytoplasm. Seems to induce apoptosis in the host cell (By similarity).

Alternative Name

Mu1

Entrez Gene ID

956448

UniProt ID

P11078

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