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Mouse Anti-MAGEA5 (AA 60-124) Recombinant Antibody (CBFYM-1313) (CBMAB-M1472-FY)

This product is mouse antibody that recognizes MAGEA5. The antibody CBFYM-1313 can be used for immunoassay techniques such as: ELISA, WB.
See all MAGEA5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-1313
Antibody Isotype
IgG2a, k
Application
ELISA, WB

Basic Information

Immunogen
Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: GPLKSPQGAS AIPTAIDFTL WRQSIKGSSN QEEEGPSTSP DPESVFRAAL SKKVADLIHF LLLKY
Specificity
Human
Antibody Isotype
IgG2a, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 60-124

Target

Full Name
melanoma antigen family A, 5
Introduction
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene. The protein is represented in this Gene record in accordance with the assumed protein-coding status defined in the literature. Read-through transcription exists between this gene and the upstream melanoma antigen family A, 10 gene.
Entrez Gene ID
4104
UniProt ID
P43359
Alternative Names
MAGE Family Member A5; Cancer/Testis Antigen Family 1, Member 5; Melanoma Antigen Family A5; Cancer/Testis Antigen 1.5; MAGE-5a Antigen; MAGE-5b Antigen; MAGE-5 Antigen
Function
May negatively regulates apoptosis.
Biological Process
Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Regulation of chromosome segregationManual Assertion Based On ExperimentIMP:HGNC
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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