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Mouse Anti-MAGEA8 (AA 1-318) Recombinant Antibody (CBFYM-1314) (CBMAB-M1473-FY)

This product is mouse antibody that recognizes MAGEA8. The antibody CBFYM-1314 can be used for immunoassay techniques such as: ELISA, IF, WB.
See all MAGEA8 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-1314
Antibody Isotype
IgG1, k
Application
ELISA, IF, WB

Basic Information

Immunogen
Full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: MLLGQKSQRY KAEEGLQAQG EAPGLMDVQI PTAEEQKAAS SSSTLIMGTL EEVTDSGSPS PPQSPEGASS SLTVTDSTLW SQSDEGSSSN EEEGPSTSPD PAHLESLFRE ALDEKVAELV RFLLRKYQIK EPVTKAEMLE S
Specificity
Human
Antibody Isotype
IgG1, k
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-318

Target

Full Name
melanoma antigen family A, 8
Introduction
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Entrez Gene ID
4107
UniProt ID
P43361
Alternative Names
MAGE Family Member A8; MAGE-8 Antigen; Cancer/Testis Antigen Family 1, Member 8; Melanoma Antigen Family A8; Cancer/Testis Antigen 1.8; MAGE8; CT1.8; Melanoma-Associated Antigen 8; Melanoma Antigen Family A, 8
Function
Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Biological Process
Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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