Mouse Anti-MAGEA9 (AA 1-315) Recombinant Antibody (CBFYM-1315) (CBMAB-M1474-FY)

Name: Mouse Anti-MAGEA9 (AA 1-315) Recombinant Antibody (CBFYM-1315)
SKU: CBMAB-M1474-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYM-1315

Application

ELISA, WB

Immunogen

Full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: MSLEQRSPHC KPDEDLEAQG EDLGLMGAQE PTGEEEETTS SSDSKEEEVS AAGSSSPPQS PQGGASSSIS VYYTLWSQFD EGSSSQEEEE PSSSVDPAQL EFMFQEALEL KVAELVHFLL HKYRVKEPVT KAEMLESVIK N

Specificity

Human

Antibody Isotype

IgM, k

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 1-315

More Infomation

Target

Full Name

MAGE Family Member A9

Introduction

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.

Entrez Gene ID

4108

UniProt ID

P43362

Alternative Names

MAGE Family Member A9; MAGE-9 Antigen; Cancer/Testis Antigen Family 1, Member 9; Melanoma-Associated Antigen 9; Melanoma Antigen Family A9; Cancer/Testis Antigen 1.9

Function

Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.

Biological Process

Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

He, H., Mi, J., Su, Y., Wang, B., Wang, W., Li, Y., & Liu, J. (2022). Analysis of the Clinical Value of MAGE-A9 Expressions in Cervical Cancer Tissues and PBMC. Emergency Medicine International, 2022.

Chu, J., Johnson, J., & Ramanathan, S. (2022). Deciphering the Role of Cancer‐Testis Antigen (CTA) MAGEA9 in Regulating DNA Repair Pathway Proteins MSH2 and MSH6. The FASEB Journal, 36.

Yu, L., Shao, X., Huo, L., & Zhang, T. (2020). Long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) promotes cell proliferation and migration by regulating miR-143-3p and MAGE family member A9 (MAGEA9) in oral squamous cell carcinoma. Medical science monitor: international medical journal of experimental and clinical research, 26, e924187-1.

Johnson, J. (2020). MAGEA9: driver or passenger in CARcinogenesis. The FASEB Journal, 34(S1), 1-1.

LIU, S., ZHAO, Y., XU, Y., SANG, M., ZHAO, R., GU, L., & SHAN, B. (2019). Expressions and clinical significances of MAGE-A9, MAGE-A11 and Ki67 in laryngeal squamous cell carcinoma. Chinese Journal of Cancer Biotherapy, 1356-1362.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

MAGEA9 Matched Antibody Pair (705) (CAT#: APMAB-705LY)

MAGEA9 Matched Antibody Pair (706) (CAT#: APMAB-706LY)

MAGEA9 Matched Antibody Pair (707) (CAT#: APMAB-707LY)

Related Products

MAGEA9 Matched Antibody Pair (707) (CAT#: APMAB-707LY)

Mouse Anti-MAGEA9 Recombinant Antibody (CBFYM-1317) (CAT#: CBMAB-M1476-FY)

Mouse Anti-MAGEA9 Recombinant Antibody (V2-620113) (CAT#: CBMAB-A5164-LY)

MAGEA9 Matched Antibody Pair (706) (CAT#: APMAB-706LY)

MAGEA9 Matched Antibody Pair (705) (CAT#: APMAB-705LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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