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Mouse Anti-MAMU-DRA Recombinant Antibody (CBFYH-3379) (CBMAB-H0800-FY)

This product is mouse antibody that recognizes MAMU-DRA. The antibody CBFYH-3379 can be used for immunoassay techniques such as: ELISA.
See all MAMU-DRA antibodies

Summary

Host Animal
Mouse
Specificity
Monkey
Clone
CBFYH-3379
Antibody Isotype
IgG
Application
ELISA

Basic Information

Immunogen
Recombinant MHCDRa (Glu28-Ile232) expressed in E. coli
Specificity
Monkey
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Major Histocompatibility Complex, Class Ii, Dr Alpha
Introduction
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
Entrez Gene ID
100187587
UniProt ID
Q6EWL5
Alternative Names
DRA; HLA-DRA; DR-alpha; Mamu-DRA1
Biological Process
Adaptive immune responseIEA:UniProtKB-KW
Antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIIEA:UniProtKB-KW
Topology
Helical: 221-242
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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