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Mouse Anti-MAPK8 Recombinant Antibody (4H5) (CBMAB-A5272-LY)

The product is antibody recognizes MAPK8. The antibody 4H5 immunoassay techniques such as: WB, ELISA.
Host Species
Mouse
Application
WB, ELISA
Immunogen
MAPK8 (NP_002741.1, 1 a.a. ~ 384 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Antibody Isotype
IgG1, κ
Specificity
Human
Clone
4H5
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
Alternative Name
JNK; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1
Entrez Gene ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-A5272-LY
Conjugates
Size
Price $
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Second antibody and isotype control