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Mouse Anti-MAPK9 Recombinant Antibody (4E13) (CBMAB-A5274-LY)

The product is antibody recognizes MAPK9. The antibody 4E13 immunoassay techniques such as: WB, ELISA.
Host Species
Mouse
Application
WB, ELISA
Immunogen
MAPK9 (AAH32539, 1 a.a. ~ 424 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Antibody Isotype
IgG1, κ
Specificity
Human
Clone
4E13
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
Alternative Name
JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; PRKM9; SAPK; p54a; p54aSAPK
Entrez Gene ID
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For research use only. Not intended for any clinical use.
Cat CBMAB-A5274-LY
Conjugates
Size
Price $
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Second antibody and isotype control