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Mouse Anti-MARCH10 Recombinant Antibody (CBCNR-601) (CBMAB-R0582-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNR-601
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL

Target

Full Name
Membrane Associated Ring-CH-Type Finger 10
Introduction
MARCH10 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Morokuma et al., 2007 [PubMed 17604280]). [supplied by OMIM, Apr 2010]
Entrez Gene ID
162333
UniProt ID
Q8NA82
Alternative Names
Membrane Associated Ring-CH-Type Finger 10; Membrane-Associated Ring Finger (C3HC4) 10, E3 Ubiquitin Protein Ligase; Membrane-Associated RING Finger Protein 10; RING-Type E3 Ubiquitin Transferase MARCH10; Membrane-Associated RING-CH Protein X; Ring Finger Protein 190; MARCH-X; RNF190;
Function
E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Biological Process
Protein ubiquitination Source: UniProtKB-UniPathway
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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