Mouse Anti-MARCH10 Recombinant Antibody (CBCNR-601) (CBMAB-R0582-CN)

Name: Mouse Anti-MARCH10 Recombinant Antibody (CBCNR-601)
SKU: CBMAB-R0582-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBCNR-601

Application

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

1 mg/mL

More Infomation

Target

Full Name

Membrane Associated Ring-CH-Type Finger 10

Introduction

MARCH10 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Morokuma et al., 2007 [PubMed 17604280]). [supplied by OMIM, Apr 2010]

Entrez Gene ID

162333

UniProt ID

Q8NA82

Alternative Names

Membrane Associated Ring-CH-Type Finger 10; Membrane-Associated Ring Finger (C3HC4) 10, E3 Ubiquitin Protein Ligase; Membrane-Associated RING Finger Protein 10; RING-Type E3 Ubiquitin Transferase MARCH10; Membrane-Associated RING-CH Protein X; Ring Finger Protein 190; MARCH-X; RNF190;

Function

E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Biological Process

Protein ubiquitination Source: UniProtKB-UniPathway

Tsai, M., Rayner, R. E., Chafin, L., Farkas, D., Adair, J., Mishan, C., ... & Londino, J. D. (2023). Influenza virus reduces ubiquitin E3 ligase MARCH10 expression to decrease ciliary beat frequency. American Journal of Physiology-Lung Cellular and Molecular Physiology, 324(5), L666-L676.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

MARCH10 Matched Antibody Pair (718) (CAT#: APMAB-718LY)

Related Products

MARCH10 Matched Antibody Pair (718) (CAT#: APMAB-718LY)

Mouse Anti-MARCH10 (AA 76-185) Recombinant Antibody (CBFYM-0493) (CAT#: CBMAB-M0621-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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