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Mouse Anti-MARCH4 Recombinant Antibody (CBFYM-1697) (CBMAB-M1864-FY)


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Summary

Host Animal
Mouse
Specificity
Mouse
Clone
CBFYM-1697
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MEMBRANE ASSOCIATED RING-CH-TYPE FINGER 4
Introduction
MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases.
Entrez Gene ID
381270
UniProt ID
Q80TE3
Alternative Names
BC056494; mKIAA1399
Function
E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Cellular Location
Golgi apparatus membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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