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Mouse Anti-MARCHF8 Recombinant Antibody (710424) (CBMAB-C3921-CN)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
710424
Antibody Isotype
IgG2b
Application
WB, ICC

Basic Information

Immunogen
E. coli-derived recombinant human MARCH8
Gln218-Val291
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS
Concentration
0.05 mg/mL

Target

Full Name
MARCHF8
Introduction
MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010]
Entrez Gene ID
Human220972
Mouse71779
Rat312656
UniProt ID
HumanQ5T0T0
MouseQ9DBD2
RatD3ZG81
Alternative Names
Membrane Associated Ring-CH-Type Finger 8; Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase; C-Mir, Cellular Modulator Of Immune Recognition; Membrane-Associated RING Finger Protein 8; RING-Type E3 Ubiquitin Transferase MARCH8; Membrane-Associated RING-CH Protein VIII; RING Finger Protein 178; MARCH-VIII; RNF178; C-MIR;
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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