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Mouse Anti-MBTPS1 Recombinant Antibody (2E6) (CBMAB-A5335-LY)

The product is antibody recognizes MBTPS1. The antibody 2E6 immunoassay techniques such as: IF, ELISA.
Host Species
Mouse
Application
IF, ELISA
Immunogen
MBTPS1 (NP_957720.1, 246 a.a. ~ 355 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Antibody Isotype
IgG1, κ
Specificity
Human
Clone
2E6
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq]
Alternative Name
KIAA0091; MGC138711; MGC138712; PCSK8; S1P; SKI-1
Entrez Gene ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-A5335-LY
Conjugates
Size
Price $
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Second antibody and isotype control