Mouse Anti-MDK Recombinant Antibody (A1055) (CBMAB-AP4491LY)

Midkine

This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

Midkine; Neurite Outgrowth-Promoting Factor 2; Neurite Growth-Promoting Factor 2; Amphiregulin-Associated Protein; Midgestation And Kidney Protein; NEGF2;

MAA631Hu22

Adrenal gland development Source: UniProtKB
Behavioral fear response Source: Ensembl
Cell differentiation Source: UniProtKB
Cerebellar granular layer development Source: Ensembl
Cerebral cortex development Source: Ensembl
Cytoskeleton organization Source: UniProtKB
Defecation Source: Ensembl
Dentate gyrus development Source: Ensembl
Estrous cycle Source: UniProtKB
Glial cell projection elongation Source: UniProtKB
Leukocyte chemotaxis involved in inflammatory response Source: UniProtKB
Negative regulation of canonical Wnt signaling pathway Source: UniProtKB
Negative regulation of cardiac muscle cell apoptotic process Source: UniProtKB
Negative regulation of cell adhesion Source: UniProtKB
Negative regulation of epithelial cell apoptotic process Source: UniProtKB
Negative regulation of inflammatory response to wounding Source: UniProtKB
Negative regulation of neuron apoptotic process Source: UniProtKB
Negative regulation of ossification Source: UniProtKB
Negative regulation of regulatory T cell differentiation Source: UniProtKB
Nervous system development Source: UniProtKB
Oogenesis Source: UniProtKB
Positive regulation of artery morphogenesis Source: UniProtKB
Positive regulation of blood vessel branching Source: UniProtKB
Positive regulation of cartilage development Source: UniProtKB
Positive regulation of cell adhesion Source: UniProtKB
Positive regulation of cell division Source: UniProtKB-KW
Positive regulation of cell migration Source: UniProtKB
Positive regulation of epithelial to mesenchymal transition Source: UniProtKB
Positive regulation of hepatocyte proliferation Source: UniProtKB
Positive regulation of inflammatory response Source: UniProtKB
Positive regulation of inflammatory response to wounding Source: UniProtKB
Positive regulation of interleukin-12 production Source: UniProtKB
Positive regulation of keratinocyte proliferation Source: UniProtKB
Positive regulation of leukocyte adhesion to vascular endothelial cell Source: UniProtKB
Positive regulation of leukocyte cell-cell adhesion Source: UniProtKB
Positive regulation of leukocyte chemotaxis Source: UniProtKB
Positive regulation of macrophage chemotaxis Source: UniProtKB
Positive regulation of neural precursor cell proliferation Source: UniProtKB
Positive regulation of neuron migration Source: UniProtKB
Positive regulation of neuron projection development Source: UniProtKB
Positive regulation of neutrophil chemotaxis Source: UniProtKB
Positive regulation of neutrophil extravasation Source: UniProtKB
Positive regulation of oligodendrocyte differentiation Source: UniProtKB
Positive regulation of smooth muscle cell chemotaxis Source: UniProtKB
Positive regulation of substrate adhesion-dependent cell spreading Source: UniProtKB
Positive regulation of T cell differentiation Source: UniProtKB
Positive regulation of transcription, DNA-templated Source: Ensembl
Positive regulation of vascular endothelial cell proliferation Source: UniProtKB
Regulation of actin cytoskeleton reorganization Source: UniProtKB
Regulation of behavior Source: Ensembl
Regulation of bone remodeling Source: UniProtKB
Regulation of chondrocyte differentiation Source: UniProtKB
Response to auditory stimulus Source: UniProtKB
Response to glucocorticoid Source: Ensembl
Response to wounding Source: UniProtKB
Response to xenobiotic stimulus Source: Ensembl
Short-term memory Source: Ensembl
Signal transduction Source: ProtInc
T cell activation involved in immune response Source: UniProtKB
Tissue regeneration Source: UniProtKB

Secreted