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Mouse Anti-MED10 Recombinant Antibody (CBWJN-1137) (CBMAB-N0956-WJ)

This product is a Mouse antibody that recognizes MED10. The antibody CBWJN-1137 can be used for immunoassay techniques such as: ELISA, WB.
See all MED10 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJN-1137
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Mediator Complex Subunit 10
Introduction
MED10 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]
Entrez Gene ID
84246
UniProt ID
Q9BTT4
Alternative Names
Mediator Complex Subunit 10; Transformation-Related Gene 17 Protein; Transformation-Related Gene 20 Protein; TRG-17; TRG-20; Mediator Of RNA Polymerase II Transcription, Subunit 10 Homolog (NUT2, S. Cerevisiae); Mediator Of RNA Polymerase II Transcription, Subunit 10;
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Biological Process
Positive regulation of transcription by RNA polymerase II Source: GO_Central
Positive regulation of transcription elongation from RNA polymerase II promoter Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: ComplexPortal
RNA polymerase II preinitiation complex assembly Source: ComplexPortal
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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