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Mouse Anti-MED30 Antibody (1B12) (CBMAB-0648-YC)

Provided herein are mouse monoclonal antibodies against Human MED30. The antibody clone 1B12 can be used for immunoassay techniques, such as ELISA, IP and WB.
See all MED30 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1B12
Antibody Isotype
IgG1
Application
ELISA, IP, WB

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MED30
Introduction
MED30 (mediator of RNA polymerase II transcription subunit 30) is a component of this complex that appears to be metazoan specific. The multiprotein TRAP/Mediator complex facilitates gene expression through a wide variety of transcriptional activators.
Entrez Gene ID
90390
UniProt ID
Q96HR3
Alternative Names
THRAP6; TRAP25
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Biological Process
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of transcription elongation from RNA polymerase II promoter Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: UniProtKB
RNA polymerase II preinitiation complex assembly Source: ComplexPortal
Stem cell population maintenance Source: Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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