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Mouse Anti-MED31 (AA 1-131) Recombinant Antibody (CBFYM-2010) (CBMAB-M2188-FY)

This product is mouse antibody that recognizes MED31. The antibody CBFYM-2010 can be used for immunoassay techniques such as: ELISA, WB.
See all MED31 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2010
Antibody Isotype
IgG2b, k
Application
ELISA, WB

Basic Information

Immunogen
Full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: MAAAVAMETD DAGNRLRFQL ELEFVQCLAN PNYLNFLAQR GYFKDKAFVN YLKYLLYWKD PEYAKYLKYP QCLHMLELLQ YEHFRKELVN AQCAKFIDEQ QILHWQHYSR KRMRLQQALA EQQQQNNTSG K
Specificity
Human
Antibody Isotype
IgG2b, k
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-131

Target

Full Name
MEDIATOR COMPLEX SUBUNIT 31
Introduction
MED31 is a Protein Coding gene. Among its related pathways are Gene Expression and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha. Gene Ontology annotations related to this gene include protein complex binding and RNA polymerase II transcription cofactor activity.
Entrez Gene ID
51003
UniProt ID
Q9Y3C7
Alternative Names
Mediator Complex Subunit 31; Mediator Complex Subunit SOH1; HSOH1; Soh1; Mediator Of RNA Polymerase II Transcription, Subunit 31 Homolog (S. Cerevisiae); Mediator Of RNA Polymerase II Transcription, Subunit 31 Homolog; Mediator Of RNA Polymerase II Transcription Subunit 31; 3110004H13Rik; CGI-125
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Biological Process
Limb development Source: Ensembl
Negative regulation of fibroblast proliferation Source: Ensembl
Positive regulation of transcription elongation from RNA polymerase II promoter Source: ComplexPortal
Positive regulation of transcription initiation from RNA polymerase II promoter Source: ComplexPortal
Regulation of transcription by RNA polymerase II Source: GO_Central
RNA polymerase II preinitiation complex assembly Source: ComplexPortal
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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