Mouse Anti-MEP1A Recombinant Antibody (CBYC-P103) (CBMAB-P0503-YC)

Name: Mouse Anti-MEP1A Recombinant Antibody (CBYC-P103)
SKU: CBMAB-P0503-YC
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBYC-P103

Antibody Isotype

IgG

Application

WB, ICC, IHC-P, IHC-Fr, ELISA

Basic Information

Immunogen

Meprin A Alpha

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

PBS, pH 7.4, 0.02% sodium azide, 50% glycerol

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Meprin A Subunit Alpha

Introduction

MEP1A (Meprin A Subunit Alpha) is a protein coding gene. Among its related pathways are Collagen chain trimerization. Gene Ontology annotations related to this gene include metalloendopeptidase activity and metallopeptidase activity. An important paralog of the gene is MEP1B.

Entrez Gene ID

4224

UniProt ID

Q16819

Alternative Names

PPHA

Cellular Location

Membrane

Topology

Extracellular: 66-712
Helical: 713-740
Cytoplasmic: 741-746

PTM

N-glycosylated; contains GlcNAc, galactose, mannose and a small amount of fucose.

More Infomation

References

Li, M., Huang, C., Wu, Y., Zhu, L., Zhang, Y., Zhou, Y., ... & Liao, W. (2023). Long non-coding RNA CCL14-AS suppresses invasiveness and lymph node metastasis of colorectal cancer cells by regulating MEP1A. Cancer Cell International, 23(1), 1-15.

Ge, W., Hou, C., Zhang, W., Guo, X., Gao, P., Song, X., ... & Wang, J. (2021). Mep1a contributes to Ang II-induced cardiac remodeling by promoting cardiac hypertrophy, fibrosis and inflammation. Journal of molecular and cellular cardiology, 152, 52-68.

Grainger, A. T., Pilar, N., Li, J., Chen, M. H., Abramson, A. M., Becker-Pauly, C., & Shi, W. (2021). Identification of Mep1a as a susceptibility gene for atherosclerosis in mice. Genetics, 219(4), iyab160.

Gao, R., Liu, D., Guo, W., Ge, W., Fan, T., Li, B., ... & Wang, J. (2020). Meprin‐α (Mep1A) enhances TNF‐α secretion by mast cells and aggravates abdominal aortic aneurysms. British journal of pharmacology, 177(12), 2872-2885.

Chen, Y., Wu, F., Zhang, L., Du, L., & Yan, X. (2020). Predictive value of MEP1A in cancer prognosis: A protocol for systematic review and meta-analysis. Medicine, 99(45).

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

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Rabbit Anti-MEP1A Recombinant Antibody (CBFYE-1552)

Mouse Anti-MEP1A Recombinant Antibody (CBFYM-0127)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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SDS
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Second antibody and isotype control

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