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Mouse Anti-METTL6 Recombinant Antibody (CBFYM-2130) (CBMAB-M2312-FY)

This product is mouse antibody that recognizes METTL6. The antibody CBFYM-2130 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all METTL6 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBFYM-2130
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
METHYLTRANSFERASE LIKE 6
Introduction
METTL6 is a Protein Coding gene. Gene Ontology annotations related to this gene include methyltransferase activity. An important paralog of this gene is METTL2B.
Entrez Gene ID
Human131965
Mouse67011
Rat290564
UniProt ID
HumanQ8TCB7
MouseQ8BVH9
RatQ6AXU8
Alternative Names
Methyltransferase Like 6; EC 2.1.1.41; EC 2.1.1.-; EC 2.1.1
Function
S-adenosyl-L-methionine-dependent methyltransferase that mediates N3-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Ser), including tRNA(Ser)(UGA) and tRNA(Ser)(GCU) (PubMed:32923617, PubMed:34922197, PubMed:34268557, PubMed:34862464).

Interaction with SARS1/SerRS is required for N3-methylcytidine methylation (PubMed:34268557).
Biological Process
tRNA methylation Source: UniProtKB
Cellular Location
Nucleus
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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