Mouse Anti-MEX3D Recombinant Antibody (CBFYM-2135) (CBMAB-M2317-FY)

Name: Mouse Anti-MEX3D Recombinant Antibody (CBFYM-2135)
SKU: CBMAB-M2317-FY
Rating: 5 (1 reviews)

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Summary

Host Animal

Mouse

Specificity

Mouse, Rat, Human

Clone

CBFYM-2135

Application

WB, IP, IF, ELISA

Basic Information

Specificity

Mouse, Rat, Human

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

MEX-3 RNA BINDING FAMILY MEMBER D

Introduction

MEX3D is a Protein Coding gene. Gene Ontology annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is MEX3B.

Entrez Gene ID

Human	399664
Mouse	237400
Rat	299613

UniProt ID

Human	Q86XN8
Mouse	Q3UE17
Rat	F1M5V7

Alternative Names

Mex-3 RNA Binding Family Member D; RING Finger And KH Domain-Containing Protein 1; Ring Finger And KH Domain Containing 1; Bcl-2 ARE RNA Binding Protein; RING Finger Protein 193; RNF193; RKHD1; TINO

Function

RNA binding protein, may be involved in post-transcriptional regulatory mechanisms.

Biological Process

mRNA destabilization Source: BHF-UCL
mRNA localization resulting in posttranscriptional regulation of gene expression Source: BHF-UCL

Cellular Location

Nucleus
Cytoplasm
Note: Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway.

PTM

Phosphorylated.

More Infomation

References

Zheng, Z., Chen, X., Cai, X., Lin, H., Xu, J., & Cheng, X. (2022). RNA-binding protein MEX3D promotes cervical carcinoma tumorigenesis by destabilizing TSC22D1 mRNA. Cell Death Discovery, 8(1), 250.

Shao, L., Wang, J., Karatas, O., & Ittmann, M. (2021). MEX3D is an oncogenic driver in prostate cancer. The Prostate, 81(15), 1202-1213.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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