Sign in or Register   Sign in or Register
  |  

Mouse Anti-MGAT4B (AA 401-500) Recombinant Antibody (CBFYM-2171) (CBMAB-M2353-FY)

This product is mouse antibody that recognizes MGAT4B. The antibody CBFYM-2171 can be used for immunoassay techniques such as: ELISA, IF, WB.
See all MGAT4B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2171
Antibody Isotype
IgG1, k
Application
ELISA, IF, WB

Basic Information

Immunogen
Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: AEVSTSLKTY QHFTLEKAYL REDFFWAFTP AAGDFIRFRF FQPLRLERFF FRSGNIEHPE DKLFNTSVEV LPFDNPQSDK EALQEGRTAT LRYPRSPDGY
Specificity
Human
Antibody Isotype
IgG1, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 401-500

Target

Full Name
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
Introduction
This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme A, catalyzes the transfer of N-acetylglucosamine from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation.
Entrez Gene ID
11282
UniProt ID
Q9UQ53
Alternative Names
Mannosyl (Alpha-1,3-)-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase, Isozyme B; UDP-N-Acetylglucosamine: Alpha-1,3-D-Mannoside Beta-1,4-N-Acetylglucosaminyltransferase IVb; Mannosyl (Alpha-1,3-)-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase, Isoenzyme B; N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase IVb; N-Acetylglucosaminyltransferase IVb; GlcNAc-T IVb; EC 2.4.1.145
Function
Glycosyltransferase that catalyze the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains (PubMed:17006639, PubMed:10372966).

Prefers complex-type N-glycans over hybrid-types (PubMed:17006639).

Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis (PubMed:17006639).
Biological Process
N-glycan processing Source: ProtInc
Positive regulation of protein glycosylation in Golgi Source: UniProtKB
Protein N-linked glycosylation Source: GO_Central
Viral protein processing Source: Reactome
Cellular Location
Golgi apparatus
Golgi apparatus membrane
Note: A processed soluble form also exists.
Topology
Cytoplasmic: 1-7
Helical: 8-28
Lumenal: 29-548
PTM
N-glycosylated.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-MGAT4B (AA 401-500) Recombinant Antibody (CBFYM-2171)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare