Rabbit Anti-MIOS Recombinant Antibody (CBFYM-2231) (CBMAB-M2414-FY)

Name: Rabbit Anti-MIOS Recombinant Antibody (CBFYM-2231)
SKU: CBMAB-M2414-FY
Rating: 5 (1 reviews)

See all MIOS antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

CBFYM-2231

Application

WB, IP

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Meiosis Regulator For Oocyte Development

Introduction

MIOS is a Protein Coding gene. Among its related pathways are PI3K/Akt Signaling and mTOR signaling pathway.

Entrez Gene ID

Human	54468
Mouse	252875
Rat	362324

UniProt ID

Human	Q9NXC5
Mouse	Q8VE19
Rat	D3Z9C0

Alternative Names

Meiosis Regulator For Oocyte Development; Missing Oocyte Meiosis Regulator Homolog; WD Repeat-Containing Protein Mio; Missing Oocyte, Meiosis Regulator, Homolog (Drosophila); Missing Oocyte, Meiosis Regulator, Homolog; GATOR Complex Protein MIOS

Function

As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238).

It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).

Biological Process

Cellular response to amino acid starvation Source: UniProtKB
Negative regulation of TORC1 signaling Source: ComplexPortal
Positive regulation of TORC1 signaling Source: GO_Central
Positive regulation of TOR signaling Source: SGD
Protein-containing complex localization Source: UniProtKB

Cellular Location

Lysosome membrane

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Rabbit Anti-MIOS Recombinant Antibody (CBFYM-2231)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry