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Rabbit Anti-MIS18A Recombinant Antibody (D3N2X) (CBMAB-CP1538-LY)

The product is antibody recognizes MIS18A. The antibody D3N2X immunoassay techniques such as: WB.
See all MIS18A antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
D3N2X
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg41 of human Mis18-α protein.
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
MIS18 Kinetochore Protein A
Introduction
MIS18A (MIS18 Kinetochore Protein A) is a Protein Coding gene. Diseases associated with MIS18A include Cerebral Arteritis. Among its related pathways are Chromosome Maintenance and DNA Damage.
Entrez Gene ID
54069
UniProt ID
Q9NYP9
Alternative Names
MIS18 Kinetochore Protein A; FAPP1-Associated Protein 1; C21orf45; C21orf46; FASP1; MIS18 Kinetochore Protein Homolog A (S. Pombe); Chromosome 21 Open Reading Frame 46;
Function
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Biological Process
Cell cycle Source: UniProtKB-KW
Cell division Source: UniProtKB-KW
CENP-A containing chromatin assembly Source: GO_Central
Chromosome segregation Source: GO_Central
Regulation of DNA methylation Source: Ensembl
Cellular Location
Nucleus
Other locations
Chromosome
centromere
Note: Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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