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Mouse Anti-MLC1 Recombinant Antibody (CBFYM-0655) (CBMAB-M0791-FY)

This product is mouse antibody that recognizes MLC. The antibody CBFYM-0655 can be used for immunoassay techniques such as: ELISA.
See all MLC1 antibodies

Summary

Host Animal
Mouse
Specificity
Cattle
Clone
CBFYM-0655
Antibody Isotype
IgG1
Application
ELISA

Basic Information

Specificity
Cattle
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MEGALENCEPHALIC LEUKOENCEPHALOPATHY WITH SUBCORTICAL CYSTS 1
Introduction
A reduction in milk lactose content could be beneficial for nutritional but also agricultural and industrial purposes.
Entrez Gene ID
101410076
UniProt ID
Q08E21
Alternative Names
MLC
Function
Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.
Biological Process
Caveolin-mediated endocytosis Source: UniProtKB
Cellular response to cholesterol Source: UniProtKB
Ion transport Source: UniProtKB-KW
Positive regulation of intracellular transport Source: UniProtKB
Protein transport Source: Ensembl
Regulation of response to osmotic stress Source: UniProtKB
Vesicle-mediated transport Source: UniProtKB
Cellular Location
Endoplasmic reticulum
Plasma membrane
Cell membrane
Other locations
Membrane
perinuclear region
Involvement in disease
Leukoencephalopathy, megalencephalic, with subcortical cysts, 1 (MLC1):
A syndrome of cerebral leukoencephalopathy and megalencephaly characterized by ataxia, spasticity, seizures, delay in motor development and mild mental retardation. The brain appears swollen on magnetic resonance imaging, with diffuse white-matter abnormalities and the invariable presence of subcortical cysts in frontal and temporal lobes.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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