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Mouse Anti-MMP28 Recombinant Antibody (3C11) (CBMAB-A5533-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3C11
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
MMP28 (NP_077278, 441 a.a. ~ 520 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
matrix metallopeptidase 28
Introduction
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Transcript variants encoding different isoforms have been described. [provided by RefSeq]
Entrez Gene ID
79148
UniProt ID
Q9H239
Alternative Names
EPILYSIN; MM28; MMP-28; MMP25
Function
Can degrade casein. Could play a role in tissues homeostasis and repair.
Biological Process
Collagen catabolic process Source: GO_Central
Extracellular matrix organization Source: GO_Central
Negative regulation of macrophage chemotaxis Source: Ensembl
Cellular Location
Extracellular matrix
PTM
The precursor is cleaved by a furin endopeptidase.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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