Mouse Anti-MOB2 Recombinant Antibody (CBFYM-2454) (CBMAB-M2641-FY)

This product is mouse antibody that recognizes MOB2. The antibody CBFYM-2454 can be used for immunoassay techniques such as: WB.
See all MOB2 antibodies

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYM-2454

Antibody Isotype

IgG1

Application

Basic Information

Immunogen

Recombinant human HCCA2 Protein

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

MOB KINASE ACTIVATOR 2

Introduction

The Ras/protein kinase A pathway acts in parallel with the Mob2/Cbk1 pathway to effect cell cycle progression and proper bud site selection.

Entrez Gene ID

81532

UniProt ID

Q70IA6

Alternative Names

MOB Kinase Activator 2; Mps One Binder Kinase Activator-Like 2; HCCA2; MOB2 Mps One Binder Homolog (Yeast); MOB2 Mps One Binder Homolog; Mob2 Homolog

Function

Stimulates the autophosphorylation and kinase activity of STK38 and STK38L.

Biological Process

Positive regulation of protein phosphorylation Source: GO_Central
Signal transduction Source: GO_Central

Cellular Location

Nucleus
Other locations
perinuclear region

PTM

Phosphorylated.

References

Liu, N., Wang, J., Yun, Y., Wang, J., Xu, C., Wu, S., ... & Chen, Y. (2021). The NDR kinase–MOB complex FgCot1‐Mob2 regulates polarity and lipid metabolism in Fusarium graminearum. Environmental Microbiology, 23(9), 5505-5524.

Jiang, K., Yao, G., Hu, L., Yan, Y., Liu, J., Shi, J., ... & Piao, H. (2020). MOB2 suppresses GBM cell migration and invasion via regulation of FAK/Akt and cAMP/PKA signaling. Cell Death & Disease, 11(4), 230.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-MOB2 Monoclonal Antibody (CBFYH-3294)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
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Second antibody and isotype control

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