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Mouse Anti-MOB3B Recombinant Antibody (CBFYM-2456) (CBMAB-M2643-FY)

This product is mouse antibody that recognizes MOB3B. The antibody CBFYM-2456 can be used for immunoassay techniques such as: FC, IF, WB.
See all MOB3B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2456
Antibody Isotype
IgG1
Application
FC, IF, WB

Basic Information

Immunogen
MOBKL2B antibody was raised in mouse using a full length recombinant protein of human MOBKL2B (NP_079037) produced in HEK293T cells,
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MOB KINASE ACTIVATOR 3B
Introduction
The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor gene.
Entrez Gene ID
79817
UniProt ID
Q86TA1
Alternative Names
MOB Kinase Activator 3B; Monopolar Spindle 1 Binding, MOB1, Domain Containing; Mps One Binder Kinase Activator-Like 2B; MOB Kinase Activator-Like 2B; Mob1 Homolog 2b; C9orf35
Function
Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
Biological Process
Positive regulation of protein phosphorylation Source: GO_Central
Regulation of hippo signaling Source: UniProtKB
Signal transduction Source: GO_Central
Cellular Location
Nucleus
Other locations
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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