Mouse Anti-MOB4 Recombinant Antibody (CBFYM-2458) (CBMAB-M2645-FY)

This product is mouse antibody that recognizes MOB4. The antibody CBFYM-2458 can be used for immunoassay techniques such as: WB, ELISA, IP.
See all MOB4 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYM-2458

Antibody Isotype

IgG1

Application

WB, ELISA, IP

Basic Information

Immunogen

Recombinant Human MOB4/PREI3/MOBKL3 protein

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

MOB FAMILY MEMBER 4, PHOCEIN

Introduction

This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1.

Entrez Gene ID

25843

UniProt ID

Q9Y3A3

Alternative Names

MOB Family Member 4, Phocein; Preimplantation Protein 3; Mps One Binder Kinase Activator-Like 3; Phocein, Mob-Like Protein; Class II MMOB1; Mob1 Homolog 3; MOBKL3; PREI3; PHOCN

Function

May play a role in membrane trafficking, specifically in membrane budding reactions.

Cellular Location

Golgi apparatus
Golgi stack membrane
Other locations
perinuclear region
Membrane
Note: In a perinuclear punctate pattern. Associated with membranes and the Golgi stacks.

PTM

Phosphorylated on serine residues.

References

Santos, I. B., Garrido-Maraver, J., Gonçalves, C., Oliveira, B. I., & Tavares, Á. A. (2023). Role of MOB4 in Cell Proliferation and Neurogenesis. BioChem, 3(4), 182-196.

Jahan, M., Iwasa, H., Kuroyanagi, H., & Hata, Y. (2021). Loss of Caenorhabditis elegans homologue of human MOB4 compromises life span, health life span and thermotolerance. Genes to Cells, 26(10), 798-806.

Delgado, I. L., Carmona, B., Nolasco, S., Santos, D., Leitão, A., & Soares, H. (2020). MOB: Pivotal conserved proteins in cytokinesis, cell architecture and tissue homeostasis. Biology, 9(12), 413.

Gundogdu, R., & Hergovich, A. (2019). MOB (Mps one binder) proteins in the hippo pathway and cancer. Cells, 8(6), 569.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
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