Mouse Anti-MOS Recombinant Antibody (CBFYM-0393) (CBMAB-M0495-FY)

This product is mouse antibody that recognizes MOS. The antibody CBFYM-0393 can be used for immunoassay techniques such as: WB, ELISA.
See all MOS antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Frog

Clone

CBFYM-0393

Antibody Isotype

IgG2b

Application

WB, ELISA

Basic Information

Immunogen

MBP-mos fusion protein

Specificity

Frog

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

MOS Proto-Oncogene, Serine/Threonine Kinase

Introduction

MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK .

Entrez Gene ID

100489962

UniProt ID

P12965

Alternative Names

MOS Proto-Oncogene, Serine/Threonine Kinase; V-Mos Moloney Murine Sarcoma Viral Oncogene Homolog; Oocyte Maturation Factor Mos; Proto-Oncogene C-Mos; EC 2.7.11.1; Proto-Oncogene Serine/Threonine-Protein Kinase Mos

Biological Process

Chromatin organization Source: UniProtKB
Establishment of meiotic spindle orientation Source: UniProtKB
MAPK cascade Source: UniProtKB
Meiotic spindle organization Source: UniProtKB
Negative regulation of metaphase/anaphase transition of meiotic cell cycle Source: UniProtKB
Positive regulation of MAPK cascade Source: UniProtKB
Protein autophosphorylation Source: UniProtKB
Regulation of meiotic nuclear division Source: Ensembl
Signal transduction Source: GO_Central

Cellular Location

Cytosol
Other locations
cytoplasm

References

Liu, Z., Jin, X., Miao, Y., Wang, P., Gu, Y., Shangguan, X., ... & Wang, G. (2023). Identification and Characterization of C-Mos in Pearl Mussel Hyriopsis cumingii and Its Role in Gonadal Development. Biomolecules, 13(6), 931.

Zeng, Y., Shi, J., Xu, S., Shi, R., Wu, T., Li, H., ... & Wang, L. (2022). Bi-allelic mutations in MOS cause female infertility characterized by preimplantation embryonic arrest. Human Reproduction, 37(3), 612-620.

Zhang, Y. L., Zheng, W., Ren, P., Jin, J., Hu, Z., Liu, Q., ... & Tong, X. (2022). Biallelic variants in MOS cause large polar body in oocyte and human female infertility. Human Reproduction, 37(8), 1932-1944.

Zhang, Y. L., Zheng, W., Ren, P., Hu, H., Tong, X., Zhang, S. P., ... & Zhang, S. (2021). Biallelic mutations in MOS cause female infertility characterized by human early embryonic arrest and fragmentation. EMBO Molecular Medicine, 13(12), e14887.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-MOS Recombinant Antibody (CBFYM-0409)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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