Mouse Anti-MOSPD1 Recombinant Antibody (CBFYM-2479) (CBMAB-M2666-FY)

This product is mouse antibody that recognizes MOSPD1. The antibody CBFYM-2479 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all MOSPD1 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Mouse, Rat, Human

Clone

CBFYM-2479

Application

WB, IP, IF, ELISA

Basic Information

Specificity

Mouse, Rat, Human

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

MOTILE SPERM DOMAIN CONTAINING 1

Introduction

MOSPD1 is a Protein Coding gene. Diseases associated with MOSPD1 include Conotruncal Heart Malformations. Gene Ontology annotations related to this gene include structural molecule activity. An important paralog of this gene is MOSPD3.

Entrez Gene ID

Human	56180
Mouse	70380
Rat	317312

UniProt ID

Human	Q9UJG1
Mouse	Q8VEL0
Rat	Q5RJS6

Alternative Names

Motile Sperm Domain Containing 1; Motile Sperm Domain-Containing Protein 1; DJ473B4

Function

Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation.

Biological Process

Cell differentiation Source: UniProtKB-KW
Negative regulation of transcription by RNA polymerase II Source: BHF-UCL
Positive regulation of transcription by RNA polymerase II Source: BHF-UCL

Cellular Location

Golgi apparatus
Golgi apparatus membrane
Endoplasmic reticulum
Endoplasmic reticulum membrane

References

Horie, C., Zhu, C., Yamaguchi, K., Nakagawa, S., Takane, K., Ikenoue, T., ... & Furukawa, Y. (2021). Identification of Motile Sperm Domain Containing 1 (MOSPD1) As a Novel Target of the Wnt/β-Catenin Signaling Pathway in Colorectal Cancer.

Cabukusta, B., Berlin, I., van Elsland, D. M., Forkink, I., Spits, M., de Jong, A. W., ... & Neefjes, J. (2020). Human VAPome analysis reveals MOSPD1 and MOSPD3 as membrane contact site proteins interacting with FFAT-related FFNT motifs. Cell reports, 33(10).

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
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