Mouse Anti-MPND Recombinant Antibody (CBFYM-0709) (CBMAB-M0851-FY)

Name: Mouse Anti-MPND Recombinant Antibody (CBFYM-0709)
SKU: CBMAB-M0851-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYM-0709

Application

ELISA, WB

Specificity

Human

Antibody Isotype

IgG2b, k

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

MPN DOMAIN CONTAINING

Introduction

MPND is a Protein Coding gene. Gene Ontology annotations related to this gene include peptidase activity. An important paralog of this gene is MYSM1.

Entrez Gene ID

84954

UniProt ID

Q8N594

Alternative Names

MPN Domain Containing; EC 3.4.-.-

Function

Probable protease (By similarity).

Acts as a sensor of N6-methyladenosine methylation on DNA (m6A): recognizes and binds m6A DNA, leading to its degradation (PubMed:30982744).

Biological Process

Chromatin remodeling Source: GO_Central
Positive regulation of transcription by RNA polymerase II Source: GO_Central

PTM

Degraded following binding to N6-methyladenosine methylated DNA (m6A).

Yang, M., Li, X., Tian, Z., Ma, L., Ma, J., Liu, Y., ... & Chen, Z. (2023). Structures of MPND Reveal the Molecular Recognition of Nucleosomes. International Journal of Molecular Sciences, 24(4), 3368.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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