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MPND

MPND (MPN Domain Containing) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include peptidase activity. An important paralog of this gene is MYSM1.

Full Name

MPN DOMAIN CONTAINING

Function

Probable protease (By similarity).

Acts as a sensor of N6-methyladenosine methylation on DNA (m6A): recognizes and binds m6A DNA, leading to its degradation (PubMed:30982744).

Biological Process

Chromatin remodeling Source: GO_Central
Positive regulation of transcription by RNA polymerase II Source: GO_Central

PTM

Degraded following binding to N6-methyladenosine methylated DNA (m6A).

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Anti-MPND antibodies

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Mouse Anti-MPND Recombinant Antibody (CBFYM-0709) (CBMAB-M0851-FY)

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Target: MPND

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBFYM-0709

Application*: E, WB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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