Sign in or Register   Sign in or Register
  |  

Mouse Anti-MRPL13 Recombinant Antibody (CBFYM-2554) (CBMAB-M2741-FY)

This product is mouse antibody that recognizes MRPL13. The antibody CBFYM-2554 can be used for immunoassay techniques such as: WB.
See all MRPL13 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2554
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
Full length human recombinant protein of human MRPL13 (NP_054797) produced in E. coli
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MITOCHONDRIAL RIBOSOMAL PROTEIN L13
Introduction
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
Entrez Gene ID
28998
UniProt ID
Q9BYD1
Alternative Names
Mitochondrial Ribosomal Protein L13; Mitochondrial Large Ribosomal Subunit Protein UL13m; MRP-L13; L13mt; 39S Ribosomal Protein L13, Mitochondrial; RPML13; RPL13; L13A; L13
Biological Process
Mitochondrial translation Source: ComplexPortal
Negative regulation of translation Source: GO_Central
Translation Source: UniProtKB
Cellular Location
Mitochondrion

Liang, Y., He, S., Tan, Y., Liu, Q., Zhao, F., Liu, T., ... & Zheng, S. (2024). In silico analyses of pan-squamous cell carcinoma unveiled the immunological implications of MRPL13, which had previously been under-recognized. Heliyon, 10(1).

Wang, L., Xia, Y., Zhang, Z., Liu, X., Shi, J., Wang, Y., ... & Zuo, L. (2023). High expression of MRPL13 promotes cell cycle progression and proliferation of gastric cancer cells by inhibiting p53 signaling to affect long-term prognosis. Nan Fang yi ke da xue xue bao= Journal of Southern Medical University, 43(9), 1558-1566.

Zhong, X., He, Z., Fan, Y., Yin, L., Hong, Z., Tong, Y., ... & Zhu, S. (2023). Multi-omics analysis of MRPL-13 as a tumor-promoting marker from pan-cancer to lung adenocarcinoma. Aging (Albany NY), 15(19), 10640.

Li, M., Gao, J., Zhang, H., Zhang, J., & Zhang, Y. (2023). Pan-cancer analysis of the oncogenic effects of ribosomal protein L13 (MRPL13) and validation in hepatocellular carcinoma.

Ye, H., & Zhang, N. (2021). Identification of the Upregulation of MRPL13 as a Novel Prognostic Marker Associated with Overall Survival Time and Immunotherapy Response in Breast Cancer. Computational and Mathematical Methods in Medicine, 2021.

Cai, M., Li, H., Chen, R., & Zhou, X. (2021). MRPL13 promotes tumor cell proliferation, migration and EMT process in breast cancer through the PI3K-AKT-mTOR pathway. Cancer Management and Research, 2009-2024.

Jing, C., Fu, R., Wang, C., Li, X., & Zhang, W. (2021). MRPL13 Act as a Novel Therapeutic Target and Could Promote Cell Proliferation in Non-Small Cell Lung Cancer. Cancer Management and Research, 5535-5545.

Tao, Z., Suo, H., Zhang, L., Jin, Z., Wang, Z., Wang, D., ... & Chen, B. (2020). MRPL13 is a prognostic cancer biomarker and correlates with immune infiltrates in breast cancer. OncoTargets and therapy, 12255-12268.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-MRPL13 Recombinant Antibody (CBFYM-2554)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare