Mouse Anti-MRPL15 (AA 28-296) Recombinant Antibody (CBFYM-2555) (CBMAB-M2742-FY)

This product is mouse antibody that recognizes MRPL15. The antibody CBFYM-2555 can be used for immunoassay techniques such as: WB.
See all MRPL15 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYM-2555

Antibody Isotype

IgG1

Application

Basic Information

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% Sodium azide

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 28-296

Target

Full Name

MITOCHONDRIAL RIBOSOMAL PROTEIN L15

Introduction

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q.

Entrez Gene ID

29088

UniProt ID

Q9P015

Alternative Names

Mitochondrial Ribosomal Protein L15; Mitochondrial Large Ribosomal Subunit Protein UL15m; MRP-L15; L15mt; 39S Ribosomal Protein L15, Mitochondrial; HSPC145; MRP-L7; RPML7

Biological Process

Cellular response to leukemia inhibitory factor Source: Ensembl
Mitochondrial translation Source: ComplexPortal

Cellular Location

Mitochondrion

References

Xu, H., Zou, R., Li, F., Liu, J., Luan, N., Wang, S., & Zhu, L. (2021). MRPL15 is a novel prognostic biomarker and therapeutic target for epithelial ovarian cancer. Cancer medicine, 10(11), 3655-3673.

Zeng, Y., Shi, Y., Xu, L., Zeng, Y., Cui, X., Wang, Y., ... & Zhou, Y. (2021). Prognostic value and related regulatory networks of MRPL15 in non-small-cell lung cancer. Frontiers in oncology, 11, 656172.

Gao, L., Li, J., Yan, M., & Aili, M. (2021). Methylation factor MRPL15 identified as a potential biological target in Alzheimer’s disease. Aging (Albany NY), 13(10), 13560.

Li, Q., Pang, Y., Wu, Y., Zhang, Y., & Cao, J. (2019). Effects of vitrified cryopreservation on methylation level and gene expression of GFM1 and MRPL15 in oocytes of Mongolian donkey. Animal Husbandry and Feed Science (Inner Mongolia), 40(5), 10-15.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Datasheet
SDS
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