Mouse Anti-MRPL51 Recombinant Antibody (CBFYM-0723) (CBMAB-M0865-FY)

Name: Mouse Anti-MRPL51 Recombinant Antibody (CBFYM-0723)
SKU: CBMAB-M0865-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYM-0723

Application

ELISA

Specificity

Human

Antibody Isotype

IgG2b, k

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

mitochondrial ribosomal protein L51

Introduction

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q.

Entrez Gene ID

51258

UniProt ID

Q4U2R6

Alternative Names

Mitochondrial Ribosomal Protein L51; Mitochondrial Large Ribosomal Subunit Protein ML51; Mitochondrial Ribosomal Protein 64; MRP-L51; BMRP-64; BMRP64; MRP64

Biological Process

Mitochondrial translation Source: ComplexPortal
Translation Source: GO_Central

Cellular Location

Mitochondrion

Zhang, W., Yu, L., Xu, C., Tang, T., Cao, J., Chen, L., ... & Ren, W. (2023). MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma. Oncology Letters, 26(1), 1-11.

Sahu, P. K., Salim, S., PP, M., Chauhan, S., & Tomar, R. S. (2019). Reverse genetic analysis of yeast YPR099C/MRPL51 reveals a critical role of both overlapping ORFs in respiratory growth and MRPL51 in mitochondrial DNA maintenance. FEMS Yeast Research, 19(6), foz056.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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