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Mouse Anti-MRPS28 Recombinant Antibody (CBFYM-2582) (CBMAB-M2770-FY)

This product is mouse antibody that recognizes MRPS28. The antibody CBFYM-2582 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all MRPS28 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBFYM-2582
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MITOCHONDRIAL RIBOSOMAL PROTEIN S28
Introduction
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has been called mitochondrial ribosomal protein S35 in the literature.
Entrez Gene ID
Human28957
Mouse66230
Rat689025
UniProt ID
HumanQ9Y2Q9
MouseQ9CY16
RatQ6TXG8
Alternative Names
Mitochondrial Ribosomal Protein S28; Mitochondrial Small Ribosomal Subunit Protein BS1m; 28S Ribosomal Protein S35, Mitochondrial; MRP-S28; MRP-S35; MRPS35
Biological Process
Mitochondrial translation Source: ComplexPortal
Cellular Location
Mitochondrion
Involvement in disease
Combined oxidative phosphorylation deficiency 47 (COXPD47):
An autosomal recessive, multisystemic, mitochondrial disorder characterized by intrauterine growth retardation, swallowing difficulties with failure to thrive, hypoglycemia, dehydration, and hepatomegaly. Additional features include global developmental delay with impaired intellectual development and absent speech, microcephaly, facial dysmorphism, cataract, sensorineural deafness, skeletal features, and cryptorchidism. Laboratory studies show metabolic acidosis, increased serum lactate, and variably impaired activity of mitochondrial respiratory complexes I, III, IV, and V in different tissues.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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