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Mouse Anti-MRPS7 (AA 38-242) Recombinant Antibody (CBFYM-2587) (CBMAB-M2775-FY)

This product is mouse antibody that recognizes MRPS7. The antibody CBFYM-2587 can be used for immunoassay techniques such as: WB.
See all MRPS7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2587
Antibody Isotype
IgG2a
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% Sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 38-242

Target

Full Name
MITOCHONDRIAL RIBOSOMAL PROTEIN S7
Introduction
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p.
Entrez Gene ID
UniProt ID
Alternative Names
Mitochondrial Ribosomal Protein S7; Mitochondrial Small Ribosomal Subunit Protein US7m; BMRP-27a; BMRP27a; MRP-S7; S7mt
Biological Process
Mitochondrial translation Source: UniProtKB
Ribosomal small subunit assembly Source: GO_Central
Translation Source: GO_Central
Cellular Location
Mitochondrion
Involvement in disease
Combined oxidative phosphorylation deficiency 34 (COXPD34):
An autosomal recessive disorder caused by mitochondrial dysfunction and combined respiratory chain deficiencies of complexes I, III and IV. Clinical manifestations are variable and include congenital sensorineural deafness, lactic acidemia, and progressive hepatic and renal failure.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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