Mouse Anti-MS4A7 (AA 1-241) Recombinant Antibody (CBFYM-2612) (CBMAB-M2800-FY)

Name: Mouse Anti-MS4A7 (AA 1-241) Recombinant Antibody (CBFYM-2612)
SKU: CBMAB-M2800-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYM-2612

Application

Immunogen

Full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG2b, k

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

0.5 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 1-241

More Infomation

Target

Full Name

membrane-spanning 4-domains, subfamily A, member 7

Introduction

This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Entrez Gene ID

58475

UniProt ID

Q9GZW8

Alternative Names

Membrane Spanning 4-Domains A7; Four-Span Transmembrane Protein 2; CD20 Antigen-Like 4; 4SPAN2; CD20L4; CFFM4; High Affinity Immunoglobulin Epsilon Receptor Beta Subunit

Function

May be involved in signal transduction as a component of a multimeric receptor complex.

Biological Process

Cell surface receptor signaling pathway Source: GO_Central

Cellular Location

Membrane

Topology

Cytoplasmic: 1-47
Helical: 48-68
Extracellular: 69-83
Helical: 84-104
Cytoplasmic: 105-121
Helical: 122-142
Extracellular: 143-178
Helical: 179-199
Cytoplasmic: 200-240

Ni, B., Huang, G., Yang, R., Wang, Z., Song, H., Li, K., ... & Liu, Y. (2023). The short isoform of MS4A7 is a novel player in glioblastoma microenvironment, M2 macrophage polarization, and tumor progression. Journal of Neuroinflammation, 20(1), 1-16.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-MS4A7 Recombinant Antibody (CBFYM-0732) (CAT#: CBMAB-M0874-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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