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Mouse Anti-MTRF1 Recombinant Antibody (1D5) (CBMAB-A5673-LY)

The product is antibody recognizes MTRF1. The antibody 1D5 immunoassay techniques such as: sELISA, ELISA.
See all MTRF1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1D5
Antibody Isotype
IgG2b, κ
Application
sELISA, ELISA

Basic Information

Immunogen
MTRF1 (NP_004285.2, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
mitochondrial translational release factor 1
Introduction
The protein encoded by this gene was determined by in silico methods to be a mitochondrial protein with similarity to the peptide chain release factors (RFs) discovered in bacteria and yeast. The peptide chain release factors direct the termination of translation in response to the peptide chain termination codons. Initially thought to have a role in the termination of mitochondria protein synthesis, a recent publication found no mitochondrial translation release functionality. Multiple alternatively spliced transcript variants have been suggested by mRNA and EST data; however, their full-length natures are not clear. [provided by RefSeq]
Entrez Gene ID
UniProt ID
Alternative Names
MGC47721; MRF1; MTTRF1; RF1
Function
Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain non-cognate termination stop codons AGG and AGA.
Biological Process
Mitochondrial translational termination Source: GO_Central
Regulation of translational termination Source: ProtInc
Cellular Location
Mitochondrion
PTM
Methylation of glutamine in the GGQ triplet is conserved from bacteria to mammals.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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