Mouse Anti-MUC3B Recombinant Antibody (CBFYM-2807) (CBMAB-M3000-FY)

This product is mouse antibody that recognizes MUC3B. The antibody CBFYM-2807 can be used for immunoassay techniques such as: ELISA, FC, IHC-Fr, WB.
See all MUC3B antibodies

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYM-2807

Antibody Isotype

IgG2a

Application

ELISA, FC, IHC-Fr, WB

Basic Information

Immunogen

Synthetic human MUC3 (SIB-35) peptide

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

MUCIN 3B, CELL SURFACE ASSOCIATED

Introduction

MUC3B is a Protein Coding gene. Diseases associated with MUC3B include Barrett Esophagus and Tn Polyagglutination Syndrome. Among its related pathways are Metabolism of proteins and CLEC7A signaling.

Entrez Gene ID

57876

UniProt ID

Q9H195

Alternative Names

Mucin 3B, Cell Surface Associated; Intestinal Mucin-3B; MUC-3B; Intestinal Mucin MUC3B; Mucin 3B; Mucin-3B; MUC3A; MUC3

Function

Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity).

Cellular Location

Membrane

Topology

Helical: 1141-1161

PTM

Highly O-glycosylated and probably also N-glycosylated.

References

Merikallio, H., Pincikova, T., Kotortsi, I., Karimi, R., Li, C. X., Forsslund, H., ... & Sköld, M. C. (2023). Mucins 3A and 3B Are Expressed in the Epithelium of Human Large Airway. International Journal of Molecular Sciences, 24(17), 13546.

Lang, T., & Pelaseyed, T. (2022). Discovery of a MUC3B gene reconstructs the membrane mucin gene cluster on human chromosome 7. Plos one, 17(10), e0275671.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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