Mouse Anti-MUCL1 Recombinant Antibody (CBFYM-2823) (CBMAB-M3016-FY)

This product is mouse antibody that recognizes MUCL1. The antibody CBFYM-2823 can be used for immunoassay techniques such as: WB, ICC, IHC-P, IHC-Fr, ELISA.
See all MUCL1 antibodies

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBFYM-2823

Application

WB, ICC, IHC-P, IHC-Fr, ELISA

Basic Information

Immunogen

Small Breast Epithelial Mucin

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4, 50% glycerol

Preservative

0.02% Sodium azide

Concentration

0.5 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

MUCIN LIKE 1

Introduction

MUCL1 is a Protein Coding gene. Diseases associated with MUCL1 include Breast Cancer and Tn Polyagglutination Syndrome. Among its related pathways are Metabolism of proteins and CLEC7A signaling.

Entrez Gene ID

118430

UniProt ID

Q96DR8

Alternative Names

Mucin Like 1; Small Breast Epithelial Mucin; SBEM; Mucin-Like Protein 1; Protein BS106

Function

May play a role as marker for the diagnosis of metastatic breast cancer.

Cellular Location

Secreted
Other locations
Membrane

PTM

O-glycosylated.

References

Abdulla, M., Traiki, T. B., Vaali‑Mohammed, M. A., El‑Wetidy, M. S., Alhassan, N., Al‑Khayal, K., ... & Ahmad, R. (2022). Targeting MUCL1 protein inhibits cell proliferation and EMT by deregulating β‑catenin and increases irinotecan sensitivity in colorectal cancer. International Journal of Oncology, 60(3), 1-12.

Kim, J., & Choi, H. (2022). The mucin protein MUCL1 regulates melanogenesis and melanoma genes in a manner dependent on threonine content. British Journal of Dermatology, 186(3), 532-543.

Navarro-Barriuso, J., Mansilla, M. J., Quirant-Sánchez, B., Ardiaca-Martínez, A., Teniente-Serra, A., Presas-Rodríguez, S., ... & Martínez-Cáceres, E. M. (2019). MAP7 and MUCL1 are biomarkers of Vitamin D3-induced tolerogenic dendritic cells in multiple sclerosis patients. Frontiers in immunology, 10, 1251.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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