Sign in or Register   Sign in or Register
  |  

Mouse Anti-MYO18B Recombinant Antibody (CBFYM-2980) (CBMAB-M3175-FY)

This product is mouse antibody that recognizes MYO18B. The antibody CBFYM-2980 can be used for immunoassay techniques such as: WB.
See all MYO18B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2980
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Recombinant Protein
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Myosin XVIIIB
Introduction
The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin. Mutations in this gene are associated with lung cancer.
Entrez Gene ID
84700
UniProt ID
Q8IUG5
Alternative Names
Myosin XVIIIB; Unconventional Myosin-XVIIIb; Myosin 18B; KFS4
Function
May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.
Biological Process
Cardiac muscle cell development Source: Ensembl
In utero embryonic development Source: Ensembl
Vasculogenesis Source: Ensembl
Cellular Location
Nucleus
Cytoplasm
Other locations
sarcomere
Note: Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.
Involvement in disease
Klippel-Feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism (KFS4):
A form of Klippel-Feil syndrome, a skeletal disorder characterized by congenital fusion of cervical vertebrae. It is due to a failure in the normal segmentation of vertebrae during the early weeks of fetal development. The clinical triad consists of short neck, low posterior hairline, and limited neck movement. KFS4 features additionally include myopathy, mild short stature, microcephaly, and distinctive facies.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-MYO18B Recombinant Antibody (CBFYM-2980)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare