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Mouse Anti-MYO3B (AA 280-369) Recombinant Antibody (CBFYM-2989) (CBMAB-M3184-FY)

This product is mouse antibody that recognizes MYO3B. The antibody CBFYM-2989 can be used for immunoassay techniques such as: ELISA.
See all MYO3B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYM-2989
Antibody Isotype
IgG1, k
Application
ELISA

Basic Information

Immunogen
Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: RRPSVTHLLD HPFIKGVHGK VLFLQKQLAK VLQDQKHQNP VAKTRHERMH TRRPYHVEDA EKYCLEDDLV NLEVLDEDTI IHQLQKRYAD
Specificity
Human
Antibody Isotype
IgG1, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 280-369

Target

Full Name
MYOSIN IIIB
Introduction
This gene encodes one of the class III myosins. Myosins are ATPases, activated by actin, that move along actin filaments in the cell. This class of myosins are characterized by an amino-terminal kinase domain and shown to be present in photoreceptors. Alternative splicing results in multiple transcript variants encoding different isoforms.
Entrez Gene ID
140469
UniProt ID
Q8WXR4
Alternative Names
Myosin IIIB; EC 2.7.11.1; Myosin-IIIb; EC 2.7.11
Function
Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments.
Biological Process
Cochlea morphogenesis Source: UniProtKB
Response to stimulus Source: UniProtKB-KW
Sensory perception of sound Source: UniProtKB
Visual perception Source: UniProtKB-KW
Cellular Location
Cytoskeleton
Other locations
stereocilium
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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