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Mouse Anti-NACA2 Recombinant Antibody (4H6) (CBMAB-N1052-WJ)

This product is a Mouse antibody that recognizes NACA2. The antibody 4H6 can be used for immunoassay techniques such as: ELISA, WB.
See all NACA2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4H6
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Nascent Polypeptide Associated Complex Alpha Subunit 2
Introduction
Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).
Entrez Gene ID
342538
UniProt ID
Q9H009
Alternative Names
Nascent Polypeptide Associated Complex Alpha Subunit 2; Alpha-NAC Protein; NACAL; Nascent-Polypeptide-Associated Complex Alpha Polypeptide-Like; IgE Autoantigen Alpha-Nascent Polypeptide-Associated Complex; Nascent Polypeptide-Associated Complex, Alpha Polypeptide, 2; Nascent Polypeptide-Associated Complex Subunit Alpha-Like; Nascent Polypeptide-Associated Complex Alpha Subunit 2;
Function
Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).
Biological Process
Protein targeting to membrane Source: GO_Central
Cellular Location
Nucleus
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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